By collecting samples such as abortion tissue, curettage, induction labor and other tissues, pick out fetal, embryo, or villous cells developed from fertilized eggs to extract DNA, and then perform chip analysis on them. Comprehensive detection of 46 chromosome numbers and structural abnormalities, chromosome microdeletion / duplication, loss of heterozygosity, single parent diploids, chimeras of a certain level, etc., can detect mutations <100kb.