1. What is the difference between preimplantation genetic testing / screening techniques?   

Preimplantation genetic testing is a method to diagnose genetic diseases by molecular genetics in gamete or early embryo stage. It focuses on the genetic diagnosis before embryo implantation, and obtains the embryo through in vitro fertilization. The test  starts from 1 embryonic cell in 8 cell stage or 3-5 embryonic trophoblast cells in blastocyst stage. Single cell DNA is analyzed by polymerase chain reaction (PCR) to detect gender and monogenetic diseases; or fluorescence in situ hybridization (FISH) to detect gender and chromosomal diseases. Preimplantation genetic testing is widely used in clinics for the diagnosis of monogenetic diseases, chromosomal abnormalities and so on.

Preimplantation genetic screening is to detect the complete genetic information of 23 pairs of chromosomes in early embryo and select the normal embryo before embryo transfer. The former method is to search for known single gene diseases on specific chromosomes, and the latter method is an early prenatal screening method aimed at improving the success rate of implantation. By screening for chromosome aneuploidy and selecting embryos with normal chromosome karyotype for transplantation, it can be said that PGs is a low-risk PGD.

2. What diseases can be detected by genetic testing before embryo implantation?

The pre-implantation genetic test of Unimed can diagnose any monogenetic disease with known clauses, accurately distinguish normal karyotype from balanced translocation and Robertsonian translocation embryos.

3. Pre-implantation genetic testing cycle of Unimed?

Only 2 days.