1. There is no genetic history in my family. Is it necessary to select and test cb-NIPT?

Every couple has the risk of child-bearing genetic diseases. Common genetic diseases include Down's syndrome, hemophilia A A, hemophilia B, α - thalassemia, β - thalassemia, hereditary deafness, spinal muscular atrophy, galactosemia, phenylketonuria, hepatolenticular degeneration, glycogen accumulation disease, autosomal recessive polycystic kidney, etc. These genetic diseases are manifested in the abnormalities of fetal face, limbs, intelligence, internal organs, etc. There are many genetic diseases that can not be cured so far, so it is best to prevent them by prenatal genetic testing.

2. Can cb-nipt detect Down's syndrome? In addition to Down's syndrome, what other diseases can be detected?

Sure. Down's syndrome, also known as 21 trisomy syndrome, or congenital foolishness and Down syndrome, is the first chromosome disease in human history. In China, the incidence of Down's syndrome is about 1 / 800 ~ 1 / 600, about every 20 minutes there is a child born, the probability will increase with the increasing age of pregnant women. Children with congenital mental retardation, growth retardation, often accompanied by facial features, limbs and other deformities. So far, this kind of disease can not be cured.

In addition to Down's syndrome, cb-nipt can detect all genetic variations associated with known genetic diseases.

3. What are the advantages of cb-NIPT compared with other non-invasive prenatal genetic testing?

The cb-NIPT of Unimed is a complete fetal cell, which can get the complete genome information of the fetus, so it can detect more diseases than other non-invasive prenatal gene detection.

At the same time, other non-invasive prenatal gene detection objects are the mixture of maternal and fetal free DNA, which can only detect Down's syndrome (T21), Edwin's syndrome (T18) and padao's syndrome (T13) three chromosome aneuploidy diseases by statistical method excluding maternal DNA interference. At the same time, this method is not suitable for detection of: 21 -, 18 - and 13 trisomic syndrome Structural abnormalities such as chimerism, microdeletion and microduplication; pregnant women with multiple births; pregnant women with malignant tumors; pregnant women themselves are patients with chromosomal aneuploidy; pregnant women have received allogeneic blood transfusion, transplantation, stem cell treatment, and lymphocyte immunotherapy for their spouses or relatives.

4. The best test pregnancy week is a few weeks, not in the scope can we continue to test it?

In theory, it can be tested at 10 + weeks of pregnancy. Considering the national policy and related ethical issues, it is recommended to test pregnancy for 10-24 weeks.